Side effects of mammosite breast therapy

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Some women with breast cancer will need radiation, often in addition to other treatments. The need for radiation depends on what type of surgery you had, whether your cancer has spread to the lymph nodes or somewhere else in your body, and in some cases, your age. Tumors that are large or involve the skin might also need radiation.

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PURPOSE: We present the results of the initial clinical testing of the MammoSite balloon breast brachytherapy applicator in women with early-stage breast cancer treated with breast-conserving therapy. Fifty-four patients were implanted, and 43 patients were ultimately eligible for and received brachytherapy as the sole radiation modality after lumpectomy. A dose of 34 Gy was delivered in 10 fractions over 5 days prescribed to 1 cm from the applicator surface using Ir high-dose-rate brachytherapy.

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After your cancerous lump is removed, radiation therapy may be needed. You might feel like you're in for a long haul. You remember the days when your life was pretty typical, and although it seemed like nothing much changed—it has.

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The radiation therapist will escort you into the treatment room. The therapist will help you onto the treatment table and help place you in the correct treatment position. Once the therapist is sure you are positioned correctly, he or she will leave the room and start the radiation treatment. You will be under constant observation during the treatment.

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Mammosite partial breast irradiation PBI is a targeted "internal" radiation therapy given to patients with early-stage breast cancer who choose to have lumpectomies. The FDA-approved PBI system delivers high-dose radiation directly to the site where a tumor has been removed, targeting the area where the cancer would most likely recur. PBI represents the next generation of internal radiation therapy.

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The rate of long-term complications such as palpable masses and telangiectasias was nearly five times higher in women who had MammoSite therapy, compared with those who underwent whole breast radiation therapy, results from a retrospective study showed. The incidence of palpable masses at the site of the lumpectomy, telangiectasias, and local recurrence were the studied endpoints. No significant differences existed between the study groups regarding age average was

Researchers are studying internal radiation, sometimes called partial-breast radiation or brachytherapy, for use after lumpectomy to see how the benefits compare to the current standard of external radiation to the whole breast. Internal radiation methods typically use small pieces of radioactive material, called seeds, which are placed in the area around where the cancer was. The seeds emit radiation into the surrounding tissue.

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Commonly, MammoSite is used following lumpectomy as a breast conservation strategy. For some women, it is an alternative to mastectomy removal of the entire breast. MammoSite targets the area where cancer recurrence is most likely to develop.

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Here, at the UCLA Radiation Oncology Division of Brachytherapy, we are committed to making your cancer treatment a comfortable and successful experience. With over 30 years of experience. We have some of the most expertise on the use of HDR Brachytherapy for breast cancer in the nation.

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